Your wish is its command. For years, futurists have dreamed of machines that can read minds, then act on instructions as they are thought. Now, human trials are set to begin on a brain-computer interface involving implants. Food and Drug Administration has approved a clinical trial in which four-square-millimeter chips will be placed beneath the skulls of paralyzed patients. If successful, the chips could allow patients to command a computer to act -- merely by thinking about the instructions they wish to send.