The brain changes, as all life changes, through Natural Selection, and subatomic forces in the universe creating mutations. All life is bombarded by forces in the physical world. Infinite possibilites (Edelman) enable infinite Natural Selection. Successful survival breeds reproduction. Choice is a human and questionable metaphor. Exercise is signaled by the demand of success of a neuron's dendrites and myeline growth. Repetition strengthens power and brain growth. Reasoning is a self-serving cycle of human construct.